— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人被開立靜脈注射萬古黴素（Vancomycin），護理師在輸注期間需監測哪種反應？
A client is prescribed intravenous vancomycin. Which manifestation should the nurse monitor for during the infusion?
- ASevere abdominal cramping嚴重腹部絞痛
- BFlushing of the face and neck✓ 正解面部和頸部潮紅
- CDevelopment of a dry cough出現乾咳
- DBradycardia and hypotension心動過緩與低血壓
— Explanation · 中文詳解 —
萬古黴素輸注速度過快時，常見「紅人症候群（Red Man Syndrome）」，特徵為面部、頸部與上半身出現潮紅、發癢或紅斑。這是因組織胺釋放引起的類過敏反應，而非真正過敏。處理方式為暫停輸注，減慢滴速並評估症狀。
When vancomycin is infused too rapidly, 'Red Man Syndrome' often occurs, characterized by flushing, itching, or erythema of the face, neck, and upper body. This is a pseudo-allergic reaction caused by histamine release rather than a true allergy. Management involves temporarily stopping the infusion, slowing the rate, and reassessing symptoms.
✦ 台美臨床差異
台灣醫院常針對 Vancomycin 監測波谷濃度（Trough level），美國亦同，但對輸注速度的規範較為一致。