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藥理與非經腸給藥 · MEDIUM · SATA

病人正在接受萬古黴素(Vancomycin)靜脈輸注。下列哪些徵象顯示可能出現「紅人症候群」?(選所有適合的)

A client is receiving vancomycin IV. Which assessment findings indicate potential 'Red Man Syndrome'? (Select all that apply.)

  • AHypotension✓ 正解
    低血壓
  • BFlushing of the face and neck✓ 正解
    面部和頸部潮紅
  • CPruritus✓ 正解
    皮膚搔癢
  • DRespiratory distress
    呼吸困難
  • EGeneralized urticaria
    全身性蕁麻疹
Explanation · 中文詳解

紅人症候群是因輸注過快導致組織胺大量釋放。臨床表現為臉部、頸部與上軀幹潮紅、低血壓與皮膚癢。D(呼吸窘迫)與 E(全身蕁麻疹)通常為嚴重的過敏反應(Anaphylaxis),非紅人症候群之特徵。處理原則為暫停輸注,待症狀改善後調慢輸注速率。

Red Man Syndrome is caused by massive histamine release due to rapid infusion. Clinical manifestations include flushing of the face, neck, and upper torso, hypotension, and pruritus. Options D (respiratory distress) and E (generalized urticaria) are typically seen in true anaphylaxis rather than in Red Man Syndrome. Management consists of stopping the infusion and, once symptoms improve, restarting the infusion at a slower rate.

✦ 台美臨床差異

台美皆建議若出現紅人症候群應停止輸注,但國內部分醫療院所針對此現象的抗組織胺預防使用較為謹慎。

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