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藥理與非經腸給藥 · MEDIUM · MCQ

病人獲醫囑開立 Phenelzine (單胺氧化酶抑制劑)。護理師應指導病人避免食用哪種食物?

A client is prescribed phenelzine (an MAOI). Which food should the nurse instruct the client to avoid?

  • AAged cheese✓ 正解
    陳年乳酪
  • BSteamed chicken
    蒸雞
  • CFresh apples
    新鮮蘋果
  • DWhite rice
    白米飯
Explanation · 中文詳解

Phenelzine 屬於單胺氧化酶抑制劑(MAOI),此類藥物會抑制負責分解酪胺(Tyramine)的酵素。若攝取含高量酪胺的食物,會導致體內兒茶酚胺大量釋放,引發致命的高血壓危象(Hypertensive Crisis)。護理師在衛教時,必須提供一份「低酪胺飲食清單」,強調避免陳年、醃製、發酵或煙燻類食品。臨床思路應優先考量藥物與飲食交互作用帶來的急性安全性風險。

Phenelzine is a monoamine oxidase inhibitor (MAOI); these drugs inhibit the enzyme that metabolizes tyramine. Ingesting high-tyramine foods causes massive catecholamine release and can precipitate a life-threatening hypertensive crisis. The nurse must teach a low-tyramine diet, emphasizing avoidance of aged, cured, fermented, or smoked foods. The clinical priority is preventing acute safety risks from drug-food interactions.

✦ 台美臨床差異

台美臨床對於 MAOI 的飲食衛教原則一致,但在美國臨床,護理師常需提供病人詳細的「Avoid List」小卡,因為美國飲食文化中陳年乳酪與熟成肉品(Charcuterie)極為普遍,風險暴露率較高。

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