— 藥理與非經腸給藥 · EASY · MCQ —
護理師準備給予心房顫動病人 Warfarin。給藥前應檢查哪項實驗室數值？
A nurse is preparing to administer warfarin to a client with atrial fibrillation. Which laboratory value should the nurse review before administering the dose?
- APlatelet count血小板計數
- BPartial Thromboplastin Time (PTT)部分凝血活酶時間 (PTT)
- CHemoglobin and Hematocrit血紅素和血球容積比
- DInternational Normalized Ratio (INR)✓ 正解國際標準化比值 (INR)
— Explanation · 中文詳解 —
Warfarin 的藥效監測指標為凝血酶原時間的國際標準化比值（INR）。治療心房顫動的目標範圍通常在 2.0-3.0 之間。PTT 是監測 Heparin 的指標，血小板則是監測肝素誘導之血小板低下症（HIT）的指標，兩者均非 Warfarin 的主要監測參數。
The International Normalized Ratio (INR) is the standardized laboratory test used to monitor the therapeutic efficacy and safety of warfarin therapy. While PTT monitors heparin and platelet counts screen for heparin-induced thrombocytopenia, INR specifically reflects the extrinsic pathway of coagulation affected by warfarin.
✦ 台美臨床差異
美台臨床皆以 INR 作為調整 Warfarin 劑量的依據，護理師需確認數值才給藥。