— 藥理與非經腸給藥 · MEDIUM · MCQ —
一位第二型糖尿病病人獲處方使用二甲雙胍(metformin),給藥前護理師應優先評估下列哪項數據?
A client with type 2 diabetes mellitus is prescribed metformin. Which assessment finding should the nurse prioritize prior to administering the dose?
- ABlood pressure reading血壓讀值
- BFasting blood glucose level空腹血糖濃度
- CSerum potassium level血清鉀離子濃度
- DSerum creatinine level✓ 正解血清肌酸酐濃度
— Explanation · 中文詳解 —
二甲雙胍主要經由腎臟排泄,若病人出現腎功能異常,藥物容易蓄積體內引發乳酸中毒(Lactic Acidosis),這是此藥最嚴重的副作用。因此,監測肌酸酐與評估腎絲球過濾率是臨床用藥安全的核心要求。其他選項雖為糖尿病照護重點,但皆非導致此藥急性併發症的關鍵因子。
Metformin is contraindicated in clients with renal impairment because reduced kidney function increases the risk of lactic acidosis, a serious complication. Therefore, checking serum creatinine levels is the priority assessment before administration to ensure patient safety.
✦ 台美臨床差異
台灣醫院系統常有自動偵測系統,若肌酸酐數值異常,電腦會警示護理師,但護理師仍需具備臨床判斷能力。