— 藥理與非經腸給藥 · MEDIUM · MCQ —
病人正在進行肝素連續輸注。護理師應監測哪項實驗室數值以評估治療效果？
A client is receiving a continuous heparin infusion. Which laboratory value should the nurse monitor to evaluate the therapeutic effect?
- AActivated partial thromboplastin time (aPTT)✓ 正解活化部分凝血活酶時間 (aPTT)
- BInternational normalized ratio (INR)國際標準化比值 (INR)
- CProthrombin time (PT)凝血酶原時間 (PT)
- DPlatelet count血小板計數
— Explanation · 中文詳解 —
肝素（Heparin）主要透過拮抗凝血因子來達到抗凝血作用，臨床評估其療效與劑量調整的黃金標準為 aPTT。PT 及 INR 是針對口服抗凝血劑 Warfarin 的監測指標；血小板計數雖重要（預防肝素誘發之血小板減少症 HIT），但非評估其抗凝血效力之首選。
The activated partial thromboplastin time (aPTT) is the standard laboratory test used to monitor the therapeutic effect of continuous heparin infusions. While prothrombin time (PT) and international normalized ratio (INR) are used to monitor warfarin therapy, and platelet counts are checked to detect heparin-induced thrombocytopenia, aPTT specifically evaluates the anticoagulant efficacy of heparin.
✦ 台美臨床差異
美台兩地臨床醫護皆嚴格依照 Nomogram 根據 aPTT 調整肝素流速。